RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality
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چکیده
IMMUNOLOGY AND INFLAMMATION Correction for “RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality,” by Lingjun Meng, Wei Jin, and Xiaodong Wang, which appeared in issue 35, September 1, 2015, of Proc Natl Acad Sci USA (112:11007–11012; first published August 17, 2015; 10.1073/pnas.1514730112). The authors note that on page 11010, left column, fifth full paragraph, line 3, “CD11c-CD11b” should instead appear as “CD11c-CD11b.”
منابع مشابه
Correction for Meng et al., RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality.
Systematic inflammation contributes to the development of many diseases, including cardiovascular disease, which is the leading cause of mortality worldwide. How such inflammation is initiated and maintained throughout the course of disease remains unclear. In the current study, we report the observation of specific phosphorylation of the receptor-interacting protein 3 (RIP3) kinase that marks ...
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Programmed necrosis is a form of caspase-independent cell death whose molecular regulation is poorly understood. The kinase RIP1 is crucial for programmed necrosis, but also mediates activation of the prosurvival transcription factor NF-kappaB. We postulated that additional molecules are required to specifically activate programmed necrosis. Using a RNA interference screen, we identified the ki...
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تاریخ انتشار 2015